RU-Min-Cu Tri Hair Max Serum
Triple-action hair regrowth serum combining 5% RU58841, 5% Minoxidil, and 5% GHK-Cu in a single dropper bottle. A one-of-a-kind tri-power formula designed to address hair thinning from multiple pathways. 30 mL (1 fl oz) glass dropper bottle.
Compound Profile
Pharmaceutical Data Sheet
Mechanism of Action
How RU-Min-Cu Tri Hair Max Serum Works
This formulation combines three extensively researched compounds targeting different mechanisms of androgenic alopecia: RU58841 (androgen receptor antagonist), Minoxidil (vasodilator/potassium channel opener), and GHK-Cu (growth factor modulator). This multi-target approach addresses androgen blockade, vasodilation, and growth factor stimulation simultaneously.
- Competitive androgen receptor antagonist
- Minimal systemic absorption (topical)
- Comparable efficacy to finasteride in macaque models
- Blocks DHT-mediated follicle miniaturization
- ATP-sensitive potassium channel opener
- Increases blood flow to dermal papilla
- Extends anagen (growth) phase
- Stimulates VEGF expression and angiogenesis
- Upregulates follicular growth factors
- ECM remodeling around follicles
- Anti-inflammatory properties
- Wnt/ฮฒ-catenin pathway modulation
RU58841 competitively binds androgen receptors in dermal papilla cells without significant systemic absorption. Minoxidil extends the anagen phase via VEGF stimulation. GHK-Cu provides complementary growth factor signaling โ creating a comprehensive 3-pathway approach.
Journal of Steroid Biochemistry and Molecular Biology. Topical RU58841 prevented testosterone-induced hair regression in preclinical models.
Preclinical Findings
Research Models
Clinical Data
Comparable Efficacy to Finasteride โ Topical Only
RU58841 showed comparable efficacy to finasteride in the stumptail macaque model with minimal systemic absorption. Minoxidil confirmed by meta-analysis of 11 RCTs to produce significant hair regrowth vs placebo.
J Steroid Biochemistry (2014), JAMA Dermatology (2020). Topical androgen receptor antagonism and minoxidil efficacy.
Macaque model + meta-analysis of 11 RCTs
Research Outcomes
Key Research Success Metrics
Safety Profile
Research Safety Notes
- RU58841 showed minimal systemic absorption in pharmacokinetic studies
- Minoxidil has decades of clinical safety data in topical use
- GHK-Cu naturally occurring in plasma with extensive safety literature
- Multi-compound interactions studied in combination formulation research
RU-Min-Cu Tri Hair Max Serum is a topical research formulation. For research use only.
About RU-Min-Cu Tri Hair Max Serum
Triple-action hair regrowth serum combining 5% RU58841, 5% Minoxidil, and 5% GHK-Cu in a single dropper bottle. A one-of-a-kind tri-power formula designed to address hair thinning from multiple pathways. 30 mL (1 fl oz) glass dropper bottle.
